Thursday, March 2, 2017

10:45 AM - 12:15 PM

Salon 2

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Details

A5 - The Essential Role of Growth Deficiency in the Diagnosis of Fetal Alcohol Spectrum Disorder Susan Astley, Julia Bledsoe, Julian Davies Analyses of 1,814 University of Washington patients with prenatal alcohol exposure confirms the role of growth deficiency (GD) in the diagnosis of FASD. GD was: significantly correlated with alcohol; as prevalent as the FAS facial features and CNS abnormalities; and highly correlated with and predictive of severe CNS dysfunction. Individuals with GD had a 2 to 3-fold increased risk for severe CNS dysfunction. GD accurately predicted which infants/toddlers presented with severe CNS dysfunction later in childhood Learning Objectives: 1. Understand that GD is significantly correlated with prenatal alcohol exposure after control for other risk factors including tobacco 2. Understand that GD is as prevalent as the other core FASD diagnostic features (the FAS facial features and CNS abnormalities) with 33% presenting < 10th percentile. The most prevalent form of GD is postnatal short stature 3. Understand that GD presents along the full spectrum of FASD diagnoses and increases in prevalence with increasing severity of diagnosis 4. Understand that GD is highly correlated with severe CNS dysfunction and is as strong a predictor of severe CNS dysfunction as the FAS facial phenotype